Rokiprim^®

solution for infusion

250 ml contain
800 mg Sulfametrole and
160 mg Trimethoprim

Properties

• Broad antimicrobial spectrum¹
• Excellent tissue penetration²
• Good efficacy against multiresistant bacteria and opportunistic microbes in immunocompromised patients (Pneumocystis jirovecii, Stenotrophomonas maltophilia, Burkholderia spp)

Indications

• Urinary tract and renal infections
• Gastrointestinal infections: typhus, paratyphus A and B, diarrhoea (only if caused by enterotoxigenic Escherichia coli)
• Treatment of choice (both, primary and secondary) of pneumonia caused by pneumocystis jirovecii (carinii)
• Alternative treatment option for otorhinolaryngologic infections and respiratory tract infections: acute exacerbation of chronic bronchitis, otitis media
• Alternative treatment option for infection of the female and male genital organs including gonorrhoea
• Alternative treatment option for skin infections (with multiresistant staphylococci)

¹ Vouloumanou E et al. International Journal of Antimicrobial Agents 2011; 38: 197–216

² Livermore DM et al. J. Antimicrob. Chemother. 2014;

Use

Adults:

• Standard dosage: 2 x 250 ml daily (at intervals of 12 hours)
• Intensive therapy for severe infections: 3 x 250 ml daily (at intervals of 8 hours